# DNA Library Prep Apps on Callisto

Any sequencer  |  Any chemistry  |  One platform

Callisto™ simplifies DNA library preparation by bringing short- and long-read workflows onto one flexible, app-based sample prep platform.

Each App is fully validated for performance, enabling you to prepare high-quality libraries with minimal hands-on time.

These Apps are designed for whole genome sequencing (WGS) and whole exome sequencing (WES), supporting a broad range of chemistries and sequencing platforms to give your lab complete workflow flexibility.

[Connect with an App Specialist](https://voltalabs.com/contact)

## Key Callisto Advantages

### One Platform, Every Workflow

Consolidate short- and long-read applications into a single sample prep system.

### Trusted Performance

Validated Apps deliver consistent results across whole-genome and whole-exome workflows.

### Hands-Off Efficiency

Start a run and walk away — Callisto handles the rest.

### Future-Ready

New Apps continuously expand your capabilities as new kits and chemistries emerge.

## Callisto workflow

## DNA Library Prep App Menu

### Apps

| App Name | Compatible Sequencing Platforms | Required Kits |
|----------|-------------------------------|----------------|
| [DNA EF Library Prep (powered by Watchmaker)](https://voltalabs.com/apps/dna-library-prep-for-illumina) | Illumina/Ultima/Element | All consumables (reagents included) from Volta Labs. |
| QIAseq FX DNA Library Prep | Illumina/Ultima/Element | Callisto consumables from Volta Labs. Reagents from chemistry provider. |
| Twist EF 2.0 DNA Library Prep | Illumina/Ultima/Element | Callisto consumables from Volta Labs. Reagents from chemistry provider. |
| NEB Ultra II FS DNA Library Prep | Illumina/Ultima/Element | Callisto consumables from Volta Labs. Reagents from chemistry provider. |
| IIlumina DNA PCR-Free Prep | Illumina | Callisto consumables from Volta Labs. Reagents from chemistry provider. |
| [ONT LSK114 DNA Library Prep](https://www.voltalabs.com/apps/dna-library-prep-for-oxford-nanopore-lsk114) | Oxford Nanopore | Callisto consumables from Volta Labs. Reagents from chemistry provider. |
| [PacBio SMRTbell® 3.0 DNA Library Prep](https://www.voltalabs.com/apps/pacbio-smrtbell-3-0-library-prep) | PacBio | Callisto consumables from Volta Labs. Reagents from chemistry provider. |

## Trusted by Leading Clinical Labs  around the world

“Callisto's walk-away automation, powered by advanced digital fluidics, is truly a game-changer. It allows our clinical technicians to simply load 24 DNA samples and produce clinical-grade sequencing-ready libraries seamlessly in <3 hours.”

Marcel Nelen  
UMC Utrecht

High-quality whole genome sequencing starts with better sample prep.

From research to clinical genomics, labs can unify short-read and long-read sequencing prep on a single platform.

[Connect to an App Specialist](https://voltalabs.com/contact) [Explore Callisto](https://voltalabs.com/the-callisto-system)